The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

dual specificity mitogen-activated protein kinase kinase 1
Synonyms

map kinase kinase 1

mapkk 1

mek1

mapk/erk kinase 1

ec 2.7.12.2

erk activator kinase 1

ID

http://purl.obolibrary.org/obo/dinto_2311

binds

http://purl.obolibrary.org/obo/dinto_DB08208

http://purl.obolibrary.org/obo/dinto_DB07101

http://purl.obolibrary.org/obo/dinto_DB06892

http://purl.obolibrary.org/obo/dinto_DB03115

http://purl.obolibrary.org/obo/dinto_DB07046

http://purl.obolibrary.org/obo/dinto_DB02152

http://purl.obolibrary.org/obo/dinto_DB08130

Definition

Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases

definition source

DrugBank Database

Gene

map2k1

is binded by

http://purl.obolibrary.org/obo/CHEBI_75991

http://purl.obolibrary.org/obo/CHEBI_75998

http://purl.obolibrary.org/obo/CHEBI_39112

is inhibited by

http://purl.obolibrary.org/obo/CHEBI_75991

http://purl.obolibrary.org/obo/CHEBI_39112

http://purl.obolibrary.org/obo/CHEBI_75998

is pharmacological target of

http://purl.obolibrary.org/obo/CHEBI_75991

http://purl.obolibrary.org/obo/CHEBI_75998

label

dual specificity mitogen-activated protein kinase kinase 1

OrganismClass

human

prefixIRI

obo2:dinto_2311

prefLabel

dual specificity mitogen-activated protein kinase kinase 1

related with

http://purl.obolibrary.org/obo/dinto_DB08208

http://purl.obolibrary.org/obo/dinto_DB07101

http://purl.obolibrary.org/obo/dinto_DB06892

http://purl.obolibrary.org/obo/dinto_DB03115

http://purl.obolibrary.org/obo/dinto_DB07046

http://purl.obolibrary.org/obo/dinto_DB02152

http://purl.obolibrary.org/obo/dinto_DB08130

Synonym

map kinase kinase 1

mapkk 1

mek1

mapk/erk kinase 1

ec 2.7.12.2

erk activator kinase 1

xref

UniProt ID:Q02750

DrugBank:990

subClassOf

http://purl.obolibrary.org/obo/dinto_000128

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