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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_2310
http://purl.obolibrary.org/obo/dinto_2310
|
|---|---|
| Preferred Name | protein tyrosine kinase 2 beta |
| Synonyms |
ec 2.7.10.2
related adhesion focal tyrosine kinase
cak beta
cell adhesion kinase beta
raftk
proline-rich tyrosine kinase 2
fadk 2
calcium-dependent tyrosine kinase
cadtk
focal adhesion kinase 2
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | protein tyrosine kinase 2 beta
|
|---|---|
| label | protein tyrosine kinase 2 beta
|
| Definition | Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. May represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage-gated potassium channel protein Kv1.2. Its activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity. Involved in osmotic stress-dependent SNCA 'Tyr-125' phosphorylation
|
| type | |
| Synonym |
ec 2.7.10.2
related adhesion focal tyrosine kinase
cak beta
cell adhesion kinase beta
raftk
proline-rich tyrosine kinase 2
fadk 2
calcium-dependent tyrosine kinase
cadtk
focal adhesion kinase 2
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|
| OrganismClass | human
|
| xref |
DrugBank:992
UniProt ID:Q14289
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| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_2310
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| related with | |
| is blocked by | |
| Gene | ptk2b
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| subClassOf |
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