The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_2165 http://purl.obolibrary.org/obo/dinto_2165
Preferred Name	plasminogen activator inhibitor 1
Synonyms	pai pai-1 endothelial plasminogen activator inhibitor plasminogen activator inhibitor 1 precursor
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	plasminogen activator inhibitor 1
label	plasminogen activator inhibitor 1
Definition	This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis
type	http://www.w3.org/2002/07/owl#Class
Synonym	pai pai-1 endothelial plasminogen activator inhibitor plasminogen activator inhibitor 1 precursor
OrganismClass	human
xref	DrugBank:267 UniProt ID:P05121
definition source	DrugBank Database
prefixIRI	obo2:dinto_2165
related with	http://purl.obolibrary.org/obo/dinto_DB00009 http://purl.obolibrary.org/obo/dinto_DB00029 http://purl.obolibrary.org/obo/dinto_DB00013 http://purl.obolibrary.org/obo/dinto_DB00031 http://purl.obolibrary.org/obo/dinto_DB00055 http://purl.obolibrary.org/obo/dinto_DB00015 See more See less
is pharmacological target of	http://purl.obolibrary.org/obo/dinto_DB00013
is blocked by	http://purl.obolibrary.org/obo/CHEBI_9753
Gene	serpine1
subClassOf	http://purl.obolibrary.org/obo/dinto_000128

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