The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

peroxisome proliferator-activated receptor gamma
Synonyms

ppar-gamma
ID

http://purl.obolibrary.org/obo/dinto_2153
Definition

Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis
definition source

DrugBank Database
Gene

pparg
is activated by

http://purl.obolibrary.org/obo/dinto_DB00912

http://purl.obolibrary.org/obo/dinto_DB01252

http://purl.obolibrary.org/obo/dinto_DB00731

http://purl.obolibrary.org/obo/CHEBI_9334

http://purl.obolibrary.org/obo/dinto_DB08915

http://purl.obolibrary.org/obo/CHEBI_8228

http://purl.obolibrary.org/obo/dinto_DB01067

http://purl.obolibrary.org/obo/CHEBI_28364

http://purl.obolibrary.org/obo/CHEBI_6775

http://purl.obolibrary.org/obo/CHEBI_50122

http://purl.obolibrary.org/obo/CHEBI_267413

http://purl.obolibrary.org/obo/CHEBI_47612

http://purl.obolibrary.org/obo/CHEBI_9753
is pharmacological target of

http://purl.obolibrary.org/obo/CHEBI_9434

http://purl.obolibrary.org/obo/CHEBI_9334

http://purl.obolibrary.org/obo/dinto_DB08915

http://purl.obolibrary.org/obo/CHEBI_8228

http://purl.obolibrary.org/obo/CHEBI_28364

http://purl.obolibrary.org/obo/CHEBI_6775

http://purl.obolibrary.org/obo/CHEBI_50122

http://purl.obolibrary.org/obo/CHEBI_267413

http://purl.obolibrary.org/obo/CHEBI_47612

http://purl.obolibrary.org/obo/CHEBI_9753
label

peroxisome proliferator-activated receptor gamma
OrganismClass

human
prefixIRI

obo2:dinto_2153
prefLabel

peroxisome proliferator-activated receptor gamma
related with

http://purl.obolibrary.org/obo/dinto_DB07675

http://purl.obolibrary.org/obo/dinto_DB08402

http://purl.obolibrary.org/obo/dinto_DB07209

http://purl.obolibrary.org/obo/CHEBI_9434

http://purl.obolibrary.org/obo/dinto_DB08435

http://purl.obolibrary.org/obo/dinto_DB07172

http://purl.obolibrary.org/obo/dinto_DB07509

http://purl.obolibrary.org/obo/CHEBI_49662

http://purl.obolibrary.org/obo/dinto_DB07111

http://purl.obolibrary.org/obo/dinto_DB06908

http://purl.obolibrary.org/obo/dinto_DB07724

http://purl.obolibrary.org/obo/dinto_DB08121

http://purl.obolibrary.org/obo/dinto_DB08760

http://purl.obolibrary.org/obo/dinto_DB07723

http://purl.obolibrary.org/obo/dinto_DB07208

http://purl.obolibrary.org/obo/dinto_DB07053

http://purl.obolibrary.org/obo/CHEBI_5855

http://purl.obolibrary.org/obo/dinto_DB07302

http://purl.obolibrary.org/obo/dinto_DB04689

http://purl.obolibrary.org/obo/dinto_DB07842

http://purl.obolibrary.org/obo/dinto_DB07863

http://purl.obolibrary.org/obo/dinto_DB08560

http://purl.obolibrary.org/obo/dinto_DB06926

http://purl.obolibrary.org/obo/dinto_DB04270

http://purl.obolibrary.org/obo/dinto_DB08302
Synonym

ppar-gamma
xref

DrugBank:238

UniProt ID:P37231
subClassOf

http://purl.obolibrary.org/obo/dinto_000128
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