The Drug-Drug Interactions Ontology - peroxisome proliferator-activated receptor gamma - Classes | NCBO BioPortal

The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_2153 http://purl.obolibrary.org/obo/dinto_2153
Preferred Name	peroxisome proliferator-activated receptor gamma
Synonyms	ppar-gamma
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	peroxisome proliferator-activated receptor gamma
label	peroxisome proliferator-activated receptor gamma
Definition	Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis
type	http://www.w3.org/2002/07/owl#Class
is activated by	http://purl.obolibrary.org/obo/dinto_DB00912 http://purl.obolibrary.org/obo/dinto_DB01252 http://purl.obolibrary.org/obo/dinto_DB00731 http://purl.obolibrary.org/obo/CHEBI_9334 http://purl.obolibrary.org/obo/dinto_DB08915 http://purl.obolibrary.org/obo/CHEBI_8228 http://purl.obolibrary.org/obo/dinto_DB01067 http://purl.obolibrary.org/obo/CHEBI_28364 http://purl.obolibrary.org/obo/CHEBI_6775 http://purl.obolibrary.org/obo/CHEBI_50122 http://purl.obolibrary.org/obo/CHEBI_267413 http://purl.obolibrary.org/obo/CHEBI_47612 http://purl.obolibrary.org/obo/CHEBI_9753 See more See less
Synonym	ppar-gamma
OrganismClass	human
xref	DrugBank:238 UniProt ID:P37231
definition source	DrugBank Database
prefixIRI	obo2:dinto_2153
related with	http://purl.obolibrary.org/obo/dinto_DB07675 http://purl.obolibrary.org/obo/dinto_DB08402 http://purl.obolibrary.org/obo/dinto_DB07209 http://purl.obolibrary.org/obo/CHEBI_9434 http://purl.obolibrary.org/obo/dinto_DB08435 http://purl.obolibrary.org/obo/dinto_DB07172 http://purl.obolibrary.org/obo/dinto_DB07509 http://purl.obolibrary.org/obo/CHEBI_49662 http://purl.obolibrary.org/obo/dinto_DB07111 http://purl.obolibrary.org/obo/dinto_DB06908 http://purl.obolibrary.org/obo/dinto_DB07724 http://purl.obolibrary.org/obo/dinto_DB08121 http://purl.obolibrary.org/obo/dinto_DB08760 http://purl.obolibrary.org/obo/dinto_DB07723 http://purl.obolibrary.org/obo/dinto_DB07208 http://purl.obolibrary.org/obo/dinto_DB07053 http://purl.obolibrary.org/obo/CHEBI_5855 http://purl.obolibrary.org/obo/dinto_DB07302 http://purl.obolibrary.org/obo/dinto_DB04689 http://purl.obolibrary.org/obo/dinto_DB07842 http://purl.obolibrary.org/obo/dinto_DB07863 http://purl.obolibrary.org/obo/dinto_DB08560 http://purl.obolibrary.org/obo/dinto_DB06926 http://purl.obolibrary.org/obo/dinto_DB04270 http://purl.obolibrary.org/obo/dinto_DB08302 See more See less
is pharmacological target of	http://purl.obolibrary.org/obo/CHEBI_9434 http://purl.obolibrary.org/obo/CHEBI_9334 http://purl.obolibrary.org/obo/dinto_DB08915 http://purl.obolibrary.org/obo/CHEBI_8228 http://purl.obolibrary.org/obo/CHEBI_28364 http://purl.obolibrary.org/obo/CHEBI_6775 http://purl.obolibrary.org/obo/CHEBI_50122 http://purl.obolibrary.org/obo/CHEBI_267413 http://purl.obolibrary.org/obo/CHEBI_47612 http://purl.obolibrary.org/obo/CHEBI_9753 See more See less
Gene	pparg
subClassOf	http://purl.obolibrary.org/obo/dinto_000128

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