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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_2099
http://purl.obolibrary.org/obo/dinto_2099
|
|---|---|
| Preferred Name | apoptosis regulator bcl-2 |
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | apoptosis regulator bcl-2
|
|---|---|
| label | apoptosis regulator bcl-2
|
| Definition | Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1)
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| type | |
| is modulated by | |
| is inhibited by | |
| OrganismClass | human
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| xref |
UniProt ID:P10415
DrugBank:273
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_2099
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| related with | |
| is pharmacological target of | |
| Gene | bcl2
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |