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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_2058
http://purl.obolibrary.org/obo/dinto_2058
|
|---|---|
| Preferred Name | cytochrome p450 2c9 |
| Synonyms |
cypiic9
ec 1.14.13.80
p450 mp-4/mp-8
s- mephenytoin 4-hydroxylase
(s)- limonene 7-monooxygenase
(r)-limonene 6-monooxygenase
(s)-limonene 6-monooxygenase
p450 pb-1
p-450mp
ec 1.14.13.48
ec 1.14.13.49
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | cytochrome p450 2c9
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|---|---|
| label | cytochrome p450 2c9
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| is induced by |
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| metabolizes |
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| Definition | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. This enzyme contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S- warfarin, diclofenac, phenytoin, tolbutamide and losartan
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| type | |
| is inhibited by |
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|
| Synonym |
cypiic9
ec 1.14.13.80
p450 mp-4/mp-8
s- mephenytoin 4-hydroxylase
(s)- limonene 7-monooxygenase
(r)-limonene 6-monooxygenase
(s)-limonene 6-monooxygenase
p450 pb-1
p-450mp
ec 1.14.13.48
ec 1.14.13.49
See more
See less
|
| OrganismClass | human
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| xref |
DrugBank:4757
UniProt ID:P11712
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| definition source | DrugBank Database
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| prefixIRI | obo2:dinto_2058
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| related with | |
| Gene | cyp2c9
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |