The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_2048 http://purl.obolibrary.org/obo/dinto_2048
Preferred Name	dimethylaniline monooxygenase [n-oxide-forming] 3
Synonyms	hepatic flavin-containing monooxygenase 3 fmo 3 fmo ii fmo form 2 dimethylaniline oxidase 3
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	dimethylaniline monooxygenase [n-oxide-forming] 3
label	dimethylaniline monooxygenase [n-oxide-forming] 3
metabolizes	http://purl.obolibrary.org/obo/CHEBI_49960 http://purl.obolibrary.org/obo/CHEBI_41774 http://purl.obolibrary.org/obo/CHEBI_520985 http://purl.obolibrary.org/obo/CHEBI_3699 http://purl.obolibrary.org/obo/CHEBI_7735 http://purl.obolibrary.org/obo/CHEBI_4325 http://purl.obolibrary.org/obo/CHEBI_3766 http://purl.obolibrary.org/obo/dinto_DB00582 http://purl.obolibrary.org/obo/CHEBI_49375 See more See less
Definition	Involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. It N-oxygenates primary aliphatic alkylamines as well as secondary and tertiary amines. Plays an important role in the metabolism of trimethylamine (TMA), via the production of TMA N-oxide (TMAO). Is also able to perform S-oxidation when acting on sulfide compounds
type	http://www.w3.org/2002/07/owl#Class
Synonym	hepatic flavin-containing monooxygenase 3 fmo 3 fmo ii fmo form 2 dimethylaniline oxidase 3
OrganismClass	human
xref	UniProt ID:P31513 DrugBank:6101
definition source	DrugBank Database
prefixIRI	obo2:dinto_2048
Gene	fmo3
subClassOf	http://purl.obolibrary.org/obo/dinto_000130

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