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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_1953
http://purl.obolibrary.org/obo/dinto_1953
|
|---|---|
| Preferred Name | calcium-activated potassium channel subunit beta-4 |
| Synonyms |
k(vca)beta-4
slo-beta-4
bk channel subunit beta-4
bkbeta4
hbeta4
calcium-activated potassium channel, subfamily m subunit beta-4
charybdotoxin receptor subunit beta-4
maxi k channel subunit beta-4
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | calcium-activated potassium channel subunit beta-4
|
|---|---|
| label | calcium-activated potassium channel subunit beta-4
|
| Definition | Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Decreases the gating kinetics and calcium sensitivity of the KCNMA1 channel, but with fast deactivation kinetics. May decrease KCNMA1 channel openings at low calcium concentrations but increases channel openings at high calcium concentrations. Makes KCNMA1 channel resistant to 100 nM charybdotoxin (CTX) toxin concentrations
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| type | |
| is inhibited by | |
| Synonym |
k(vca)beta-4
slo-beta-4
bk channel subunit beta-4
bkbeta4
hbeta4
calcium-activated potassium channel, subfamily m subunit beta-4
charybdotoxin receptor subunit beta-4
maxi k channel subunit beta-4
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|
| OrganismClass | human
|
| xref |
UniProt ID:Q86W47
DrugBank:6933
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| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_1953
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| Gene | kcnmb4
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |