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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_1923
http://purl.obolibrary.org/obo/dinto_1923
|
|---|---|
| Preferred Name | g protein-activated inward rectifier potassium channel 1 |
| Synonyms |
potassium channel, inwardly rectifying subfamily j member 3
girk1
inward rectifier k(+) channel kir3.1
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | g protein-activated inward rectifier potassium channel 1
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|---|---|
| label | g protein-activated inward rectifier potassium channel 1
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| Definition | This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat
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| type | |
| is inhibited by | |
| Synonym |
potassium channel, inwardly rectifying subfamily j member 3
girk1
inward rectifier k(+) channel kir3.1
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| OrganismClass | human
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| xref |
UniProt ID:P48549
DrugBank:1571
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| definition source | DrugBank Database
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| prefixIRI | obo2:dinto_1923
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| Gene | kcnj3
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| subClassOf |
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