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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
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Id | http://purl.obolibrary.org/obo/dinto_1878
http://purl.obolibrary.org/obo/dinto_1878
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Preferred Name | cytochrome c |
Type | http://www.w3.org/2002/07/owl#Class |
All Properties
label | cytochrome c
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prefLabel | cytochrome c
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Definition | Plays a role in apoptosis. Suppression of the anti- apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases
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definition source | DrugBank Database
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prefixIRI | obo2:dinto_1878
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binds |
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type | |
xref |
UniProt ID:P99999
DrugBank:1507
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OrganismClass | human
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Gene | cycs
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