The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_1874 http://purl.obolibrary.org/obo/dinto_1874
Preferred Name	peroxisome proliferator-activated receptor delta
Synonyms	nuclear hormone receptor 1 nuc1 ppar-delta ppar- beta nuci
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	peroxisome proliferator-activated receptor delta
label	peroxisome proliferator-activated receptor delta
Definition	Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Decreases expression of NPC1L1 once activated by a ligand
type	http://www.w3.org/2002/07/owl#Class
is activated by	http://purl.obolibrary.org/obo/CHEBI_28364 http://purl.obolibrary.org/obo/CHEBI_50861 http://purl.obolibrary.org/obo/CHEBI_47612
Synonym	nuclear hormone receptor 1 nuc1 ppar-delta ppar- beta nuci
OrganismClass	human
xref	UniProt ID:Q03181 DrugBank:1502
definition source	DrugBank Database
prefixIRI	obo2:dinto_1874
related with	http://purl.obolibrary.org/obo/CHEBI_9352 http://purl.obolibrary.org/obo/dinto_DB08078 http://purl.obolibrary.org/obo/dinto_DB07724 http://purl.obolibrary.org/obo/dinto_DB07070 http://purl.obolibrary.org/obo/dinto_DB07691 http://purl.obolibrary.org/obo/dinto_DB04801 http://purl.obolibrary.org/obo/dinto_DB03338 See more See less
is pharmacological target of	http://purl.obolibrary.org/obo/CHEBI_28364 http://purl.obolibrary.org/obo/CHEBI_50861 http://purl.obolibrary.org/obo/CHEBI_47612
Gene	ppard
subClassOf	http://purl.obolibrary.org/obo/dinto_000128

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