The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_1850 http://purl.obolibrary.org/obo/dinto_1850
Preferred Name	udp-glucuronosyltransferase 2b4
Synonyms	udpgth-1 hlug25 hyodeoxycholic acid udpgt 2b4
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	udp-glucuronosyltransferase 2b4
label	udp-glucuronosyltransferase 2b4
metabolizes	http://purl.obolibrary.org/obo/CHEBI_16714 http://purl.obolibrary.org/obo/CHEBI_17303 http://purl.obolibrary.org/obo/CHEBI_5855 http://purl.obolibrary.org/obo/CHEBI_5130 http://purl.obolibrary.org/obo/CHEBI_73274
Definition	UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4- nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid
type	http://www.w3.org/2002/07/owl#Class
Synonym	udpgth-1 hlug25 hyodeoxycholic acid udpgt 2b4
OrganismClass	human
xref	DrugBank:6180 UniProt ID:P06133
definition source	DrugBank Database
prefixIRI	obo2:dinto_1850
Gene	ugt2b4
subClassOf	http://purl.obolibrary.org/obo/dinto_000130

Delete	Subject	Author	Type	Created
No notes to display