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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_1812
http://purl.obolibrary.org/obo/dinto_1812
|
|---|---|
| Preferred Name | multidrug and toxin extrusion protein 1 |
| Synonyms |
mate-1
solute carrier family 47 member 1
hmate-1
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | multidrug and toxin extrusion protein 1
|
|---|---|
| label | multidrug and toxin extrusion protein 1
|
| Definition | Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes
|
| type | |
| transports | |
| is inhibited by | |
| Synonym |
mate-1
solute carrier family 47 member 1
hmate-1
|
| OrganismClass | human
|
| xref |
DrugBank:6154
UniProt ID:Q96FL8
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_1812
|
| related with | |
| Gene | slc47a1
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |