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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_1810
http://purl.obolibrary.org/obo/dinto_1810
|
|---|---|
| Preferred Name | atp-binding cassette transporter sub-family c member 11 |
| Synonyms |
multidrug resistance-associated protein 8
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | atp-binding cassette transporter sub-family c member 11
|
|---|---|
| label | atp-binding cassette transporter sub-family c member 11
|
| Definition | Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides. Enhances the cellular extrusion of cAMP and cGMP. Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate. Probably functions to secrete earwax
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| type | |
| transports | |
| is inhibited by | |
| Synonym | multidrug resistance-associated protein 8
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| OrganismClass | human
|
| xref |
UniProt ID:Q96J66
DrugBank:6155
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| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_1810
|
| Gene | abcc11
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| subClassOf |
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