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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_1670
http://purl.obolibrary.org/obo/dinto_1670
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|---|---|
| Preferred Name | sodium channel protein type 5 subunit alpha |
| Synonyms |
voltage-gated sodium channel subunit alpha nav1.5
sodium channel protein, cardiac muscle alpha-subunit
hh1
sodium channel protein type v subunit alpha
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | sodium channel protein type 5 subunit alpha
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|---|---|
| label | sodium channel protein type 5 subunit alpha
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| Definition | This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant Na(+) channel isoform. This channel is responsible for the initial upstroke of the action potential in the electrocardiogram
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| Synonym |
voltage-gated sodium channel subunit alpha nav1.5
sodium channel protein, cardiac muscle alpha-subunit
hh1
sodium channel protein type v subunit alpha
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| OrganismClass | human
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| xref |
UniProt ID:Q14524
DrugBank:220
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| definition source | DrugBank Database
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| prefixIRI | obo2:dinto_1670
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| is pharmacological target of |
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| is blocked by | |
| Gene | scn5a
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| subClassOf |
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