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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_1656
http://purl.obolibrary.org/obo/dinto_1656
|
|---|---|
| Preferred Name | sodium channel protein type 11 subunit alpha |
| Synonyms |
sodium channel protein type xi subunit alpha
peripheral nerve sodium channel 5
hnan
voltage-gated sodium channel subunit alpha nav1.9
sensory neuron sodium channel 2
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | sodium channel protein type 11 subunit alpha
|
|---|---|
| label | sodium channel protein type 11 subunit alpha
|
| Definition | This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Also involved, with the contribution of the receptor tyrosine kinase NTRK2, in rapid BDNF-evoked neuronal depolarization
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| type | |
| is inhibited by | |
| Synonym |
sodium channel protein type xi subunit alpha
peripheral nerve sodium channel 5
hnan
voltage-gated sodium channel subunit alpha nav1.9
sensory neuron sodium channel 2
|
| OrganismClass | human
|
| xref |
DrugBank:215
UniProt ID:Q9UI33
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| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_1656
|
| is pharmacological target of | |
| Gene | scn11a
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| subClassOf |
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