The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	thymidylate synthase
Synonyms	ec 2.1.1.45 ts tsase
ID	http://purl.obolibrary.org/obo/dinto_1622
binds	http://purl.obolibrary.org/obo/dinto_DB03541 http://purl.obolibrary.org/obo/dinto_DB08479 http://purl.obolibrary.org/obo/dinto_DB08734 http://purl.obolibrary.org/obo/dinto_DB08478 http://purl.obolibrary.org/obo/dinto_DB03800 http://purl.obolibrary.org/obo/CHEBI_60761 http://purl.obolibrary.org/obo/dinto_DB07577 http://purl.obolibrary.org/obo/dinto_DB01643 http://purl.obolibrary.org/obo/dinto_DB04530 http://purl.obolibrary.org/obo/CHEBI_46345
Definition
definition source	DrugBank Database
Gene	tyms
has substrate	http://purl.obolibrary.org/obo/CHEBI_44185 http://purl.obolibrary.org/obo/CHEBI_46345
is binded by	http://purl.obolibrary.org/obo/CHEBI_31348 http://purl.obolibrary.org/obo/dinto_DB00650 http://purl.obolibrary.org/obo/CHEBI_63616 http://purl.obolibrary.org/obo/CHEBI_63722 http://purl.obolibrary.org/obo/CHEBI_75179 http://purl.obolibrary.org/obo/CHEBI_60761 http://purl.obolibrary.org/obo/dinto_DB00293 http://purl.obolibrary.org/obo/dinto_DB00440 http://purl.obolibrary.org/obo/CHEBI_63723 http://purl.obolibrary.org/obo/CHEBI_71223 http://purl.obolibrary.org/obo/CHEBI_46345 http://purl.obolibrary.org/obo/CHEBI_175901 http://purl.obolibrary.org/obo/CHEBI_44185
is inhibited by	http://purl.obolibrary.org/obo/CHEBI_31348 http://purl.obolibrary.org/obo/dinto_DB00650 http://purl.obolibrary.org/obo/CHEBI_63616 http://purl.obolibrary.org/obo/CHEBI_63722 http://purl.obolibrary.org/obo/CHEBI_75179 http://purl.obolibrary.org/obo/CHEBI_175901 http://purl.obolibrary.org/obo/dinto_DB00293 http://purl.obolibrary.org/obo/dinto_DB00440 http://purl.obolibrary.org/obo/CHEBI_63723 http://purl.obolibrary.org/obo/CHEBI_71223
is pharmacological target of	http://purl.obolibrary.org/obo/CHEBI_31348 http://purl.obolibrary.org/obo/dinto_DB00650 http://purl.obolibrary.org/obo/CHEBI_63616 http://purl.obolibrary.org/obo/CHEBI_63722 http://purl.obolibrary.org/obo/CHEBI_75179 http://purl.obolibrary.org/obo/CHEBI_60761 http://purl.obolibrary.org/obo/dinto_DB00293 http://purl.obolibrary.org/obo/dinto_DB00440 http://purl.obolibrary.org/obo/CHEBI_63723 http://purl.obolibrary.org/obo/CHEBI_71223 http://purl.obolibrary.org/obo/CHEBI_46345
label	thymidylate synthase
metabolizes	http://purl.obolibrary.org/obo/CHEBI_44185 http://purl.obolibrary.org/obo/CHEBI_46345
OrganismClass	human
prefixIRI	obo2:dinto_1622
prefLabel	thymidylate synthase
related with	http://purl.obolibrary.org/obo/dinto_DB03541 http://purl.obolibrary.org/obo/dinto_DB08479 http://purl.obolibrary.org/obo/dinto_DB08734 http://purl.obolibrary.org/obo/dinto_DB08478 http://purl.obolibrary.org/obo/dinto_DB03800 http://purl.obolibrary.org/obo/CHEBI_60761 http://purl.obolibrary.org/obo/dinto_DB07577 http://purl.obolibrary.org/obo/dinto_DB01643 http://purl.obolibrary.org/obo/dinto_DB04530 http://purl.obolibrary.org/obo/CHEBI_46345
Synonym	ec 2.1.1.45 ts tsase
xref	UniProt ID:P04818 DrugBank:359
subClassOf	http://purl.obolibrary.org/obo/dinto_000130 http://purl.obolibrary.org/obo/dinto_000128

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/OMIT_0014785	OMIT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D013940	RH-MESH	LOOM
http://purl.obolibrary.org/obo/NCIT_C17199	BERO	LOOM
http://purl.uniprot.org/uniprot/P04818	FTC	LOOM
http://purl.jp/bio/4/id/200906089162113981	IOBC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#12241	OCHV	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17199	NCIT	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0040085	OCHV	LOOM
http://purl.bioontology.org/ontology/CSP/2963-9288	CRISP	LOOM
http://purl.bioontology.org/ontology/SNMI/F-68268	SNMI	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00020790	PMAPP-PMO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D08.811.913.555.500.862	RH-MESH	LOOM
http://id.nlm.nih.gov/mesh/D013940	MDM	LOOM
http://www.co-ode.org/ontologies/galen#ThymidylateSynthase	GALEN	LOOM
http://purl.obolibrary.org/obo/MESH_D013940	BERO	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/6937006	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/MESH/D013940	MESH	LOOM
http://purl.obolibrary.org/obo/PR_000016876	PR	LOOM
http://purl.obolibrary.org/obo/PR_000016876	INBANCIDO	LOOM
http://purl.obolibrary.org/obo/PR_000016876	CIDO	LOOM
http://purl.obolibrary.org/obo/PR_000016876	NIFSTD	LOOM