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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_1534
http://purl.obolibrary.org/obo/dinto_1534
|
|---|---|
| Preferred Name | cytochrome p450 26a1 |
| Synonyms |
retinoic acid-metabolizing cytochrome
retinoic acid 4-hydroxylase
p450 retinoic acid-inactivating 1
hp450rai
ec 1.14.-.-
p450rai
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | cytochrome p450 26a1
|
|---|---|
| label | cytochrome p450 26a1
|
| is induced by | |
| metabolizes | |
| Definition | Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18- hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA
|
| type | |
| is inhibited by | |
| Synonym |
retinoic acid-metabolizing cytochrome
retinoic acid 4-hydroxylase
p450 retinoic acid-inactivating 1
hp450rai
ec 1.14.-.-
p450rai
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|
| OrganismClass | human
|
| xref |
DrugBank:5934
UniProt ID:O43174
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| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_1534
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| Gene | cyp26a1
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| subClassOf |
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| No notes to display |