Link to this page
The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_1451
http://purl.obolibrary.org/obo/dinto_1451
|
|---|---|
| Preferred Name | hemagglutinin |
| Synonyms |
hemagglutinin precursor
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | hemagglutinin
|
|---|---|
| label | hemagglutinin
|
| Definition | Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore
|
| type | |
| Synonym | hemagglutinin precursor
|
| OrganismClass | viral
|
| xref |
UniProt ID:P03437
DrugBank:4890
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_1451
|
| related with | |
| Gene | ha
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |