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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_1432
http://purl.obolibrary.org/obo/dinto_1432
|
|---|---|
| Preferred Name | g protein-activated inward rectifier potassium channel 2 |
| Synonyms |
bir1
inward rectifier k(+) channel kir3.2
katp-2
potassium channel, inwardly rectifying subfamily j member 6
girk2
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | g protein-activated inward rectifier potassium channel 2
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|---|---|
| label | g protein-activated inward rectifier potassium channel 2
|
| Definition | This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium
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| type | |
| is inhibited by | |
| Synonym |
bir1
inward rectifier k(+) channel kir3.2
katp-2
potassium channel, inwardly rectifying subfamily j member 6
girk2
|
| OrganismClass | human
|
| xref |
UniProt ID:P48051
DrugBank:1581
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_1432
|
| Gene | kcnj6
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| subClassOf |
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