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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_1419
http://purl.obolibrary.org/obo/dinto_1419
|
|---|---|
| Preferred Name | glucokinase |
| Synonyms |
hk iv
hexokinase-d
ec 2.7.1.2
hk4
hexokinase type iv
hexokinase-4
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | glucokinase
|
|---|---|
| label | glucokinase
|
| Definition | Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage
|
| type | |
| Synonym |
hk iv
hexokinase-d
ec 2.7.1.2
hk4
hexokinase type iv
hexokinase-4
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|
| OrganismClass | human
|
| xref |
DrugBank:1675
UniProt ID:P35557
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_1419
|
| related with | |
| Gene | gck
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
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