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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
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Preferred Name | von willebrand factor | |
Synonyms |
von willebrand factor precursor vwf |
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ID |
http://purl.obolibrary.org/obo/dinto_1315 |
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Definition |
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma
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definition source |
DrugBank Database
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Gene |
vwf
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is binded by | ||
is pharmacological target of | ||
label |
von willebrand factor
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OrganismClass |
human
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prefixIRI |
obo2:dinto_1315
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prefLabel |
von willebrand factor
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Synonym |
von willebrand factor precursor vwf
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xref |
DrugBank:1635 UniProt ID:P04275
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subClassOf |
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