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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_1273
http://purl.obolibrary.org/obo/dinto_1273
|
|---|---|
| Preferred Name | oxysterols receptor lxr-alpha |
| Synonyms |
nuclear receptor subfamily 1 group h member 3
liver x receptor alpha
nuclear orphan receptor lxr-alpha
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | oxysterols receptor lxr-alpha
|
|---|---|
| label | oxysterols receptor lxr-alpha
|
| Definition | Orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand- binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half- sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis
|
| type | |
| Synonym |
nuclear receptor subfamily 1 group h member 3
liver x receptor alpha
nuclear orphan receptor lxr-alpha
|
| OrganismClass | human
|
| xref |
DrugBank:6283
UniProt ID:Q13133
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_1273
|
| related with | |
| Gene | nr1h3
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |