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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
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| Preferred Name | mitogen-activated protein kinase 8 | |
| Synonyms |
c-jun n-terminal kinase 1 jnk-46 stress-activated protein kinase jnk1 |
|
| ID |
http://purl.obolibrary.org/obo/dinto_1237 |
|
| binds |
http://purl.obolibrary.org/obo/dinto_DB01782 http://purl.obolibrary.org/obo/dinto_DB07845 http://purl.obolibrary.org/obo/dinto_DB07272 http://purl.obolibrary.org/obo/dinto_DB07268 |
|
| Definition |
JNK1 isoforms display different binding patterns:beta-1 preferentially binds to c-Jun, whereas alpha-1, alpha-2, and beta- 2 have a similar low level of binding to both c-Jun or ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms
|
|
| definition source |
DrugBank Database
|
|
| Gene |
mapk8
|
|
| label |
mitogen-activated protein kinase 8
|
|
| OrganismClass |
human
|
|
| prefixIRI |
obo2:dinto_1237
|
|
| prefLabel |
mitogen-activated protein kinase 8
|
|
| related with |
http://purl.obolibrary.org/obo/dinto_DB01782 http://purl.obolibrary.org/obo/dinto_DB07845 http://purl.obolibrary.org/obo/dinto_DB07272 http://purl.obolibrary.org/obo/dinto_DB07268 |
|
| Synonym |
c-jun n-terminal kinase 1 jnk-46 stress-activated protein kinase jnk1
|
|
| xref |
UniProt ID:P45983 DrugBank:6292
|
|
| subClassOf |
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