Link to this page
The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_1229
http://purl.obolibrary.org/obo/dinto_1229
|
|---|---|
| Preferred Name | prostaglandin reductase 1 |
| Synonyms |
prg-1
15-oxoprostaglandin 13-reductase
nadp-dependent leukotriene b4 12-hydroxydehydrogenase
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | prostaglandin reductase 1
|
|---|---|
| label | prostaglandin reductase 1
|
| Definition | Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha (By similarity). Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4
|
| type | |
| Synonym |
prg-1
15-oxoprostaglandin 13-reductase
nadp-dependent leukotriene b4 12-hydroxydehydrogenase
|
| OrganismClass | human
|
| xref |
DrugBank:6297
UniProt ID:Q14914
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_1229
|
| related with | |
| Gene | ptgr1
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |