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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_1135
http://purl.obolibrary.org/obo/dinto_1135
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|---|---|
| Preferred Name | alpha-2a adrenergic receptor |
| Synonyms |
alpha-2 adrenergic receptor subtype c10
alpha-2aar
alpha-2a adrenoreceptor
alpha-2a adrenoceptor
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | alpha-2a adrenergic receptor
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|---|---|
| label | alpha-2a adrenergic receptor
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| Definition | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol
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| is activated by |
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| Synonym |
alpha-2 adrenergic receptor subtype c10
alpha-2aar
alpha-2a adrenoreceptor
alpha-2a adrenoceptor
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| OrganismClass | human
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| xref |
DrugBank:318
UniProt ID:P08913
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| definition source | DrugBank Database
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| prefixIRI | obo2:dinto_1135
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| related with |
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| is pharmacological target of |
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| is blocked by |
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| Gene | adra2a
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| subClassOf |
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