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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_1134
http://purl.obolibrary.org/obo/dinto_1134
|
|---|---|
| Preferred Name | apoptotic protease-activating factor 1 |
| Synonyms |
apaf-1
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | apoptotic protease-activating factor 1
|
|---|---|
| label | apoptotic protease-activating factor 1
|
| Definition | Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis
|
| type | |
| Synonym | apaf-1
|
| OrganismClass | human
|
| xref |
UniProt ID:O14727
DrugBank:340
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_1134
|
| related with | |
| Gene | apaf1
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |