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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_1076
http://purl.obolibrary.org/obo/dinto_1076
|
|---|---|
| Preferred Name | histone acetyltransferase pcaf |
| Synonyms |
ec 2.3.1.48
p/caf
histone acetylase pcaf
p300/cbp-associated factor
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | histone acetyltransferase pcaf
|
|---|---|
| label | histone acetyltransferase pcaf
|
| Definition | Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes
|
| type | |
| Synonym |
ec 2.3.1.48
p/caf
histone acetylase pcaf
p300/cbp-associated factor
|
| OrganismClass | human
|
| xref |
UniProt ID:Q92831
DrugBank:4573
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_1076
|
| related with | |
| Gene | kat2b
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |