The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_1018 http://purl.obolibrary.org/obo/dinto_1018
Preferred Name	glycine receptor subunit alpha-1
Synonyms	glycine receptor subunit alpha-1 precursor glycine receptor 48 kda subunit glycine receptor strychnine-binding subunit
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	glycine receptor subunit alpha-1
label	glycine receptor subunit alpha-1
Definition	The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing)
type	http://www.w3.org/2002/07/owl#Class
is activated by	http://purl.obolibrary.org/obo/CHEBI_6015 http://purl.obolibrary.org/obo/CHEBI_16236 http://purl.obolibrary.org/obo/CHEBI_4445 http://purl.obolibrary.org/obo/CHEBI_9130 http://purl.obolibrary.org/obo/dinto_DB00228 http://purl.obolibrary.org/obo/dinto_DB01028 See more See less
Synonym	glycine receptor subunit alpha-1 precursor glycine receptor 48 kda subunit glycine receptor strychnine-binding subunit
OrganismClass	human
xref	UniProt ID:P23415 DrugBank:482
definition source	DrugBank Database
prefixIRI	obo2:dinto_1018
related with	http://purl.obolibrary.org/obo/CHEBI_15428 http://purl.obolibrary.org/obo/CHEBI_16523 http://purl.obolibrary.org/obo/CHEBI_5615
is pharmacological target of	http://purl.obolibrary.org/obo/CHEBI_6015 http://purl.obolibrary.org/obo/CHEBI_16236 http://purl.obolibrary.org/obo/CHEBI_4445 http://purl.obolibrary.org/obo/CHEBI_9130 http://purl.obolibrary.org/obo/dinto_DB00228 http://purl.obolibrary.org/obo/dinto_DB01028 See more See less
is blocked by	http://purl.obolibrary.org/obo/dinto_DB00431 http://purl.obolibrary.org/obo/dinto_DB01381
Gene	glra1
subClassOf	http://purl.obolibrary.org/obo/dinto_000128

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