The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

myeloperoxidase
Synonyms

mpo

myeloperoxidase precursor

ec 1.11.1.7
ID

http://purl.obolibrary.org/obo/dinto_0859
binds

http://purl.obolibrary.org/obo/CHEBI_16347

http://purl.obolibrary.org/obo/dinto_DB01225

http://purl.obolibrary.org/obo/CHEBI_116225

http://purl.obolibrary.org/obo/CHEBI_6775
Definition

Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity
definition source

DrugBank Database
Gene

mpo
has substrate

http://purl.obolibrary.org/obo/CHEBI_17141

http://purl.obolibrary.org/obo/CHEBI_4325

http://purl.obolibrary.org/obo/CHEBI_16796

http://purl.obolibrary.org/obo/dinto_DB00062

http://purl.obolibrary.org/obo/CHEBI_31941

http://purl.obolibrary.org/obo/CHEBI_9588

http://purl.obolibrary.org/obo/CHEBI_31355
is binded by

http://purl.obolibrary.org/obo/CHEBI_3485

http://purl.obolibrary.org/obo/dinto_DB00104

http://purl.obolibrary.org/obo/CHEBI_16796

http://purl.obolibrary.org/obo/CHEBI_71941

http://purl.obolibrary.org/obo/dinto_DB00461

http://purl.obolibrary.org/obo/CHEBI_72014

http://purl.obolibrary.org/obo/CHEBI_8502

http://purl.obolibrary.org/obo/CHEBI_50749

http://purl.obolibrary.org/obo/CHEBI_27565

http://purl.obolibrary.org/obo/CHEBI_59173

http://purl.obolibrary.org/obo/CHEBI_9619

http://purl.obolibrary.org/obo/CHEBI_3478

http://purl.obolibrary.org/obo/dinto_DB04827

http://purl.obolibrary.org/obo/CHEBI_27899

http://purl.obolibrary.org/obo/CHEBI_17141

http://purl.obolibrary.org/obo/CHEBI_4325

http://purl.obolibrary.org/obo/dinto_DB00062

http://purl.obolibrary.org/obo/CHEBI_31941

http://purl.obolibrary.org/obo/CHEBI_9588

http://purl.obolibrary.org/obo/CHEBI_31355
is induced by

http://purl.obolibrary.org/obo/CHEBI_3478

http://purl.obolibrary.org/obo/dinto_DB04827

http://purl.obolibrary.org/obo/CHEBI_27899
is inhibited by

http://purl.obolibrary.org/obo/CHEBI_3485

http://purl.obolibrary.org/obo/dinto_DB00104

http://purl.obolibrary.org/obo/CHEBI_16796

http://purl.obolibrary.org/obo/CHEBI_71941

http://purl.obolibrary.org/obo/dinto_DB00461

http://purl.obolibrary.org/obo/CHEBI_72014

http://purl.obolibrary.org/obo/CHEBI_8502

http://purl.obolibrary.org/obo/CHEBI_50749

http://purl.obolibrary.org/obo/CHEBI_27565

http://purl.obolibrary.org/obo/CHEBI_59173

http://purl.obolibrary.org/obo/CHEBI_9619
label

myeloperoxidase
metabolizes

http://purl.obolibrary.org/obo/CHEBI_17141

http://purl.obolibrary.org/obo/CHEBI_4325

http://purl.obolibrary.org/obo/CHEBI_16796

http://purl.obolibrary.org/obo/dinto_DB00062

http://purl.obolibrary.org/obo/CHEBI_31941

http://purl.obolibrary.org/obo/CHEBI_9588

http://purl.obolibrary.org/obo/CHEBI_31355
OrganismClass

human
prefixIRI

obo2:dinto_0859
prefLabel

myeloperoxidase
related with

http://purl.obolibrary.org/obo/CHEBI_16347

http://purl.obolibrary.org/obo/dinto_DB01225

http://purl.obolibrary.org/obo/CHEBI_116225

http://purl.obolibrary.org/obo/CHEBI_6775
Synonym

mpo

myeloperoxidase precursor

ec 1.11.1.7
xref

UniProt ID:P05164

DrugBank:1757
subClassOf

http://purl.obolibrary.org/obo/dinto_000130

http://purl.obolibrary.org/obo/dinto_000128
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