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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_0775
http://purl.obolibrary.org/obo/dinto_0775
|
|---|---|
| Preferred Name | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 |
| Synonyms |
glcuat-p
glucuronosyltransferase-p
ec 2.4.1.135
beta-1,3-glucuronyltransferase 1
udp-glcua:glycoprotein beta- 1,3-glucuronyltransferase
glcat-p
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1
|
|---|---|
| label | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1
|
| Definition | Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo- orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity:stearoyl- sphingomyelin was the most effective, followed by palmitoyl- sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group
|
| type | |
| Synonym |
glcuat-p
glucuronosyltransferase-p
ec 2.4.1.135
beta-1,3-glucuronyltransferase 1
udp-glcua:glycoprotein beta- 1,3-glucuronyltransferase
glcat-p
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|
| OrganismClass | human
|
| xref |
DrugBank:2291
UniProt ID:Q9P2W7
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_0775
|
| related with | |
| Gene | b3gat1
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |