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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_0679
http://purl.obolibrary.org/obo/dinto_0679
|
|---|---|
| Preferred Name | dna-repair protein xrcc4 |
| Synonyms |
x-ray repair cross-complementing protein 4
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | dna-repair protein xrcc4
|
|---|---|
| label | dna-repair protein xrcc4
|
| Definition | Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends
|
| type | |
| Synonym | x-ray repair cross-complementing protein 4
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| OrganismClass | human
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| xref |
UniProt ID:Q13426
DrugBank:2888
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| definition source | DrugBank Database
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| prefixIRI | obo2:dinto_0679
|
| related with | |
| Gene | xrcc4
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |