The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Preferred Name	leukocyte elastase
Synonyms	medullasin neutrophil elastase hle bone marrow serine protease ec 3.4.21.37 human leukocyte elastase elastase-2 leukocyte elastase precursor pmn elastase
ID	http://purl.obolibrary.org/obo/dinto_0662
binds	http://purl.obolibrary.org/obo/dinto_DB00099 http://purl.obolibrary.org/obo/dinto_DB00019 http://purl.obolibrary.org/obo/dinto_DB02341
Definition	Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis
definition source	DrugBank Database
Gene	elane
is binded by	http://purl.obolibrary.org/obo/dinto_DB00058 http://purl.obolibrary.org/obo/dinto_DB03925
is inhibited by	http://purl.obolibrary.org/obo/dinto_DB03925 http://purl.obolibrary.org/obo/dinto_DB00058
is pharmacological target of	http://purl.obolibrary.org/obo/dinto_DB00058
label	leukocyte elastase
OrganismClass	human
prefixIRI	obo2:dinto_0662
prefLabel	leukocyte elastase
related with	http://purl.obolibrary.org/obo/dinto_DB00099 http://purl.obolibrary.org/obo/dinto_DB00019 http://purl.obolibrary.org/obo/dinto_DB02341
Synonym	medullasin neutrophil elastase hle bone marrow serine protease ec 3.4.21.37 human leukocyte elastase elastase-2 leukocyte elastase precursor pmn elastase
xref	UniProt ID:P08246 DrugBank:437
subClassOf	http://purl.obolibrary.org/obo/dinto_000128

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/MS_1001915	MS	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00019675	PMAPP-PMO	LOOM
http://purl.jp/bio/4/id/200906030807881291	IOBC	LOOM
http://id.nlm.nih.gov/mesh/D019272	MDM	LOOM
http://purl.uniprot.org/uniprot/P08246	FTC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D08.811.277.656.959.350.560.500	RH-MESH	LOOM
http://purl.obolibrary.org/obo/MESH_D019272	BERO	LOOM
http://purl.bioontology.org/ontology/MESH/D019272	MESH	LOOM
http://purl.bioontology.org/ontology/SNMI/F-6ADC0	SNMI	LOOM
http://purl.obolibrary.org/obo/OMIT_0019344	OMIT	LOOM
http://purl.obolibrary.org/obo/MS_1001915	MS	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D019272	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D08.811.277.656.300.760.560.500	RH-MESH	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/19277006	SNOMEDCT	LOOM