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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_0642
http://purl.obolibrary.org/obo/dinto_0642
|
|---|---|
| Preferred Name | thymidylate kinase |
| Synonyms |
thymidine monophosphate kinase
dtmp kinase
tmpk
ec 2.7.4.9
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | thymidylate kinase
|
|---|---|
| label | thymidylate kinase
|
| Definition | Catalyzes the reversible phosphorylation of deoxythymidine monophosphate (dTMP) to deoxythymidine diphosphate (dTDP), using ATP as its preferred phosphoryl donor. Situated at the junction of both de novo and salvage pathways of deoxythymidine triphosphate (dTTP) synthesis, is essential for DNA synthesis and cellular growth. Has a broad specificity for nucleoside triphosphates, being highly active with ATP or dATP as phosphate donors, and less active with ITP, GTP, CTP and UTP
|
| type | |
| Synonym |
thymidine monophosphate kinase
dtmp kinase
tmpk
ec 2.7.4.9
|
| OrganismClass | bacterial
|
| xref |
UniProt ID:O05891
DrugBank:2251
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_0642
|
| related with |
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|
| Gene | tmk
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |