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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_0621
http://purl.obolibrary.org/obo/dinto_0621
|
|---|---|
| Preferred Name | interferon-alpha/beta receptor beta chain |
| Synonyms |
ifn-alpha-rec
interferon-alpha/beta receptor beta chain precursor
ifn-r
interferon alpha/beta receptor 2
type i interferon receptor
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | interferon-alpha/beta receptor beta chain
|
|---|---|
| label | interferon-alpha/beta receptor beta chain
|
| Definition | Receptor for interferons alpha and beta. Isoform 1 and isoform 3 are directly involved in signal transduction due to their interaction with the TYR kinase, JAK1. Isoform 1 also interacts with the transcriptional factors, STAT1 and STAT2. Both forms are potent inhibitors of type I IFN activity
|
| type | |
| is activated by | |
| Synonym |
ifn-alpha-rec
interferon-alpha/beta receptor beta chain precursor
ifn-r
interferon alpha/beta receptor 2
type i interferon receptor
|
| is binded by | |
| OrganismClass | human
|
| xref |
DrugBank:428
UniProt ID:P48551
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_0621
|
| related with | |
| is pharmacological target of |
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|
| Gene | ifnar2
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |