The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Preferred Name	interleukin-1 receptor-associated kinase 4
Synonyms	irak-4 ny-ren-64 antigen
ID	http://purl.obolibrary.org/obo/dinto_0442
binds	http://purl.obolibrary.org/obo/dinto_DB08590
Definition	Required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up- regulation and mRNA stabilization. Phosphorylates IRAK1
definition source	DrugBank Database
Gene	irak4
label	interleukin-1 receptor-associated kinase 4
OrganismClass	human
prefixIRI	obo2:dinto_0442
prefLabel	interleukin-1 receptor-associated kinase 4
related with	http://purl.obolibrary.org/obo/dinto_DB08590
Synonym	irak-4 ny-ren-64 antigen
xref	DrugBank:6853 UniProt ID:Q9NWZ3
subClassOf	http://purl.obolibrary.org/obo/dinto_000128

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Mapping To	Ontology	Source
http://www.orpha.net/ORDO/Orphanet_122674	ORDO	LOOM
http://www.limics.org/hrdo/rdfns#gen_id_16266	HRDO	LOOM
http://purl.obolibrary.org/obo/PR_000001780	EFO	LOOM
http://purl.obolibrary.org/obo/PR_000001780	OBA	LOOM
http://purl.obolibrary.org/obo/PR_000001780	PR	LOOM
http://purl.obolibrary.org/obo/PR_000001780	CIDO	LOOM
http://purl.obolibrary.org/obo/PR_000001780	NIFSTD	LOOM
http://purl.bioontology.org/ontology/OMIM/606883	OMIM	LOOM
http://www.orpha.net/ORDO/Orphanet_122674	ORDO	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29752	NCIT	LOOM
http://www.drugtargetontology.org/dto/DTO_03100193	DTO	LOOM
http://purl.obolibrary.org/obo/NCIT_C29752	BERO	LOOM