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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_0383
http://purl.obolibrary.org/obo/dinto_0383
|
|---|---|
| Preferred Name | ectonucleotide pyrophosphatase/phosphodiesterase family member 1 |
| Synonyms |
e- npp 1
ec 3.6.1.9
phosphodiesterase i/nucleotide pyrophosphatase 1
nucleotide pyrophosphatase
ec 3.1.4.1
plasma-cell membrane glycoprotein pc-1
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | ectonucleotide pyrophosphatase/phosphodiesterase family member 1
|
|---|---|
| label | ectonucleotide pyrophosphatase/phosphodiesterase family member 1
|
| is induced by | |
| Definition | Has a broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. Can hydrolyze nucleoside 5' triphosphates such as ATP, GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate. Can hydrolyze diadenosine polyphosphates and 3',5'-cAMP to AMP. It may play a role in the regulation of pyrophosphate production, the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling
|
| type | |
| is inhibited by | |
| Synonym |
e- npp 1
ec 3.6.1.9
phosphodiesterase i/nucleotide pyrophosphatase 1
nucleotide pyrophosphatase
ec 3.1.4.1
plasma-cell membrane glycoprotein pc-1
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|
| OrganismClass | human
|
| xref |
UniProt ID:P22413
DrugBank:508
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| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_0383
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| Gene | enpp1
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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