loading...| Preferred Name |
mast/stem cell growth factor receptor |
|
| Synonyms |
proto-oncogene tyrosine-protein kinase kit scfr mast/stem cell growth factor receptor precursor c-kit cd117 antigen ec 2.7.10.1 |
|
| ID |
http://purl.obolibrary.org/obo/dinto_0376 |
|
| binds |
http://purl.obolibrary.org/obo/dinto_DB03431 |
|
| Definition |
This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K) |
|
| definition source |
DrugBank Database |
|
| Gene |
kit |
|
| is binded by |
http://purl.obolibrary.org/obo/CHEBI_71219 http://purl.obolibrary.org/obo/CHEBI_50924 http://purl.obolibrary.org/obo/CHEBI_68647 http://purl.obolibrary.org/obo/CHEBI_38940 http://purl.obolibrary.org/obo/CHEBI_45783 http://purl.obolibrary.org/obo/dinto_DB08901 |
|
| is blocked by |
http://purl.obolibrary.org/obo/CHEBI_52172 http://purl.obolibrary.org/obo/CHEBI_49375 http://purl.obolibrary.org/obo/CHEBI_50924 |
|
| is inhibited by |
http://purl.obolibrary.org/obo/CHEBI_71219 |
|
| is modulated by |
http://purl.obolibrary.org/obo/CHEBI_52172 http://purl.obolibrary.org/obo/CHEBI_49375 http://purl.obolibrary.org/obo/CHEBI_50924 |
|
| is pharmacological target of |
http://purl.obolibrary.org/obo/CHEBI_71219 http://purl.obolibrary.org/obo/CHEBI_50924 http://purl.obolibrary.org/obo/CHEBI_68647 |
|
| label |
mast/stem cell growth factor receptor |
|
| OrganismClass |
human |
|
| prefixIRI |
obo2:dinto_0376 |
|
| prefLabel |
mast/stem cell growth factor receptor |
|
| related with |
http://purl.obolibrary.org/obo/dinto_DB03431 |
|
| Synonym |
proto-oncogene tyrosine-protein kinase kit scfr mast/stem cell growth factor receptor precursor c-kit cd117 antigen ec 2.7.10.1 |
|
| xref |
UniProt ID:P10721 DrugBank:504 |
|
| subClassOf |