Link to this page
The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_0339
http://purl.obolibrary.org/obo/dinto_0339
|
|---|---|
| Preferred Name | bile acid receptor |
| Synonyms |
rxr-interacting protein 14
retinoid x receptor-interacting protein 14
farnesoid x-activated receptor
farnesol receptor hrr-1
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | bile acid receptor
|
|---|---|
| label | bile acid receptor
|
| Definition | Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) and activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 within its gene locus
|
| type | |
| Synonym |
rxr-interacting protein 14
retinoid x receptor-interacting protein 14
farnesoid x-activated receptor
farnesol receptor hrr-1
|
| OrganismClass | human
|
| xref |
DrugBank:3233
UniProt ID:Q96RI1
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_0339
|
| related with | |
| Gene | nr1h4
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |