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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_0267
http://purl.obolibrary.org/obo/dinto_0267
|
|---|---|
| Preferred Name | angiogenin |
| Synonyms |
angiogenin precursor
ec 3.1.27.-
ribonuclease 5
rnase 5
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | angiogenin
|
|---|---|
| label | angiogenin
|
| Definition | May function as a tRNA-specific ribonuclease that binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus, thereby promoting the endothelial invasiveness necessary for blood vessel formation. Angiogenin induces vascularization of normal and malignant tissues. Abolishes protein synthesis by specifically hydrolyzing cellular tRNAs
|
| type | |
| Synonym |
angiogenin precursor
ec 3.1.27.-
ribonuclease 5
rnase 5
|
| OrganismClass | human
|
| xref |
UniProt ID:P03950
DrugBank:2149
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_0267
|
| related with | |
| Gene | ang
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |