The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Preferred Name	low-density lipoprotein receptor
Synonyms	low-density lipoprotein receptor precursor ldl receptor
ID	http://purl.obolibrary.org/obo/dinto_0236
binds	http://purl.obolibrary.org/obo/CHEBI_60652 http://purl.obolibrary.org/obo/dinto_DB02944
Definition	Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits
definition source	DrugBank Database
Gene	ldlr
label	low-density lipoprotein receptor
OrganismClass	human
prefixIRI	obo2:dinto_0236
prefLabel	low-density lipoprotein receptor
related with	http://purl.obolibrary.org/obo/CHEBI_60652 http://purl.obolibrary.org/obo/dinto_DB02944
Synonym	low-density lipoprotein receptor precursor ldl receptor
xref	DrugBank:554 UniProt ID:P01130
subClassOf	http://purl.obolibrary.org/obo/dinto_000128

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Mapping To	Ontology	Source
http://doe-generated-ontology.com/OntoAD#C0034821	ONTOAD	LOOM
http://www.orpha.net/ORDO/Orphanet_123021	ORDO	LOOM
http://purl.uniprot.org/uniprot/P01130	FTC	LOOM
http://purl.bioontology.org/ontology/CSP/4006-0059	CRISP	LOOM
http://purl.bioontology.org/ontology/OMIM/606945	OMIM	LOOM
http://www.orpha.net/ORDO/Orphanet_123021	ORDO	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17074	NCIT	LOOM
http://purl.obolibrary.org/obo/NCIT_C17074	BERO	LOOM
http://purl.obolibrary.org/obo/PR_000009744	PR	LOOM
http://purl.obolibrary.org/obo/PR_000009744	NIFSTD	LOOM
http://www.co-ode.org/ontologies/galen#LowDensityLipoproteinReceptor	GALEN	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#10620	OCHV	LOOM