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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_0077
http://purl.obolibrary.org/obo/dinto_0077
|
|---|---|
| Preferred Name | potassium voltage-gated channel subfamily e member 1 |
| Synonyms |
delayed rectifier potassium channel subunit isk
iks producing slow voltage-gated potassium channel subunit beta mink
minimal potassium channel
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | potassium voltage-gated channel subfamily e member 1
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|---|---|
| label | potassium voltage-gated channel subfamily e member 1
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| Definition | Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr)
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| type | |
| is inhibited by | |
| Synonym |
delayed rectifier potassium channel subunit isk
iks producing slow voltage-gated potassium channel subunit beta mink
minimal potassium channel
|
| OrganismClass | human
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| xref |
DrugBank:544
UniProt ID:P15382
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| definition source | DrugBank Database
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| prefixIRI | obo2:dinto_0077
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| is pharmacological target of | |
| Gene | kcne1
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| subClassOf |
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| No notes to display |