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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_0043
http://purl.obolibrary.org/obo/dinto_0043
|
|---|---|
| Preferred Name | gamma-aminobutyric acid receptor subunit pi |
| Synonyms |
gaba(a) receptor subunit pi
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | gamma-aminobutyric acid receptor subunit pi
|
|---|---|
| label | gamma-aminobutyric acid receptor subunit pi
|
| Definition | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. In the uterus, the function of the receptor appears to be related to tissue contractility. The binding of this pI subunit with other GABA(A) receptor subunits alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone
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| type | |
| Synonym | gaba(a) receptor subunit pi
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| OrganismClass | human
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| xref |
DrugBank:6090
UniProt ID:O00591
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| definition source | DrugBank Database
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| prefixIRI | obo2:dinto_0043
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| Gene | gabrp
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| subClassOf |
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| No notes to display |