The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/CHEBI_9513 http://purl.obolibrary.org/obo/CHEBI_9513
Preferred Name	thalidomide
Synonyms	N-(2,6-dioxo-3-piperidyl)phthalimide Distaval Sedalis (+-)-thalidomide alpha-N-phthalylglutaramide N-phthalylglutamic acid imide 3-phthalimidoglutarimide K-17 (+-)-N-(2,6-dioxo-3-piperidyl)phthalimide thalidomide talidomida 2,6-dioxo-3-phthalimidopiperidine C13H10N2O4 Softenon alpha-phthalimidoglutarimide thalidomidum 2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione N-phthaloylglutamimide alpha-(N-phthalimido)glutarimide Talimol 1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline rac-2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione Thalidomide N-Phthalyl-glutaminsaeure-imid See more See less
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	thalidomide
label	thalidomide
DBSynonym	n-phthalylglutamic acid imide thalidomine usp26 n-phthalimidoglutamic acid imide n-phthaloylglutamimide alpha-phthalimidoglutarimide
ATCCode	L04AX02
Definition	A racemate comprising equimolar amounts of R- and S-thalidomide.
has effect	http://purl.obolibrary.org/obo/OAE_0000238 http://purl.obolibrary.org/obo/OAE_0000879 http://purl.obolibrary.org/obo/OAE_0000496 http://purl.obolibrary.org/obo/OAE_0000447 http://purl.obolibrary.org/obo/OAE_0001059 http://purl.obolibrary.org/obo/OAE_0000395 http://purl.obolibrary.org/obo/OAE_0000449 http://purl.obolibrary.org/obo/OAE_0000497 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0001373 http://purl.obolibrary.org/obo/OAE_0000597 http://purl.obolibrary.org/obo/OAE_0000081 http://purl.obolibrary.org/obo/OAE_0000815 http://purl.obolibrary.org/obo/OAE_0000573 http://purl.obolibrary.org/obo/OAE_0000905 http://purl.obolibrary.org/obo/OAE_0001154 http://purl.obolibrary.org/obo/OAE_0001098 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0000318 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000479 http://purl.obolibrary.org/obo/OAE_0000659 http://purl.obolibrary.org/obo/OAE_0000492 http://purl.obolibrary.org/obo/OAE_0000198 http://purl.obolibrary.org/obo/OAE_0000596 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0001046 http://purl.obolibrary.org/obo/OAE_0000825 http://purl.obolibrary.org/obo/OAE_0000443 http://purl.obolibrary.org/obo/OAE_0001186 http://purl.obolibrary.org/obo/OAE_0000921 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0000913 http://purl.obolibrary.org/obo/OAE_0000611 http://purl.obolibrary.org/obo/OAE_0000567 http://purl.obolibrary.org/obo/OAE_0000549 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000545 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0001013 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0000967 http://purl.obolibrary.org/obo/OAE_0000412 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000317 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0000482 http://purl.obolibrary.org/obo/OAE_0000333 http://purl.obolibrary.org/obo/OAE_0000197 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000250 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0001288 http://purl.obolibrary.org/obo/OAE_0001365 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0001053 http://purl.obolibrary.org/obo/OAE_0001055 http://purl.obolibrary.org/obo/OAE_0001063 http://purl.obolibrary.org/obo/OAE_0000287 http://purl.obolibrary.org/obo/OAE_0000632 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001463 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0001433 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000386 http://purl.obolibrary.org/obo/OAE_0000691 http://purl.obolibrary.org/obo/OAE_0001275 http://purl.obolibrary.org/obo/OAE_0000687 http://purl.obolibrary.org/obo/OAE_0000455 http://purl.obolibrary.org/obo/OAE_0001234 http://purl.obolibrary.org/obo/OAE_0000802 http://purl.obolibrary.org/obo/OAE_0001105 http://purl.obolibrary.org/obo/OAE_0000943 http://purl.obolibrary.org/obo/OAE_0000995 http://purl.obolibrary.org/obo/OAE_0000671 http://purl.obolibrary.org/obo/OAE_0001461 http://purl.obolibrary.org/obo/OAE_0001057 http://purl.obolibrary.org/obo/OAE_0000434 http://purl.obolibrary.org/obo/OAE_0001243 http://purl.obolibrary.org/obo/OAE_0001295 http://purl.obolibrary.org/obo/OAE_0001515 http://purl.obolibrary.org/obo/OAE_0001284 http://purl.obolibrary.org/obo/OAE_0000309 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000842 http://purl.obolibrary.org/obo/OAE_0000643 http://purl.obolibrary.org/obo/OAE_0001153 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0001106 http://purl.obolibrary.org/obo/OAE_0000184 http://purl.obolibrary.org/obo/OAE_0000533 http://purl.obolibrary.org/obo/OAE_0000542 http://purl.obolibrary.org/obo/OAE_0000341 http://purl.obolibrary.org/obo/OAE_0000894 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000038 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000438 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0002122 http://purl.obolibrary.org/obo/OAE_0001202 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000866 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000780 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0000405 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000647 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0001336 http://purl.obolibrary.org/obo/OAE_0001152 http://purl.obolibrary.org/obo/OAE_0000022 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000487 http://purl.obolibrary.org/obo/OAE_0000516 http://purl.obolibrary.org/obo/OAE_0001147 http://purl.obolibrary.org/obo/OAE_0000779 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000275 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000470 http://purl.obolibrary.org/obo/OAE_0001291 http://purl.obolibrary.org/obo/OAE_0000514 http://purl.obolibrary.org/obo/OAE_0001345 http://purl.obolibrary.org/obo/OAE_0001001 http://purl.obolibrary.org/obo/OAE_0000501 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0000242 http://purl.obolibrary.org/obo/OAE_0000211 http://purl.obolibrary.org/obo/OAE_0000462 http://purl.obolibrary.org/obo/OAE_0000466 http://purl.obolibrary.org/obo/OAE_0000358 http://purl.obolibrary.org/obo/OAE_0001309 http://purl.obolibrary.org/obo/OAE_0001035 http://purl.obolibrary.org/obo/OAE_0000618 http://purl.obolibrary.org/obo/OAE_0000500 http://purl.obolibrary.org/obo/OAE_0000456 http://purl.obolibrary.org/obo/OAE_0000534 http://purl.obolibrary.org/obo/OAE_0001044 http://purl.obolibrary.org/obo/OAE_0001458 http://purl.obolibrary.org/obo/OAE_0001364 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0001298 http://purl.obolibrary.org/obo/OAE_0000811 http://purl.obolibrary.org/obo/OAE_0000506 http://purl.obolibrary.org/obo/OAE_0000350 http://purl.obolibrary.org/obo/OAE_0000304 See more See less
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2873 http://purl.obolibrary.org/obo/dinto_2717 http://purl.obolibrary.org/obo/dinto_3490 http://purl.obolibrary.org/obo/dinto_0792 http://purl.obolibrary.org/obo/dinto_1586
induces	http://purl.obolibrary.org/obo/dinto_2990
inhibits	http://purl.obolibrary.org/obo/dinto_3490 http://purl.obolibrary.org/obo/dinto_0291 http://purl.obolibrary.org/obo/dinto_1586
type	http://www.w3.org/2002/07/owl#Class
has role	http://purl.obolibrary.org/obo/CHEBI_35705 http://purl.obolibrary.org/obo/CHEBI_50905 http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_50919 http://purl.obolibrary.org/obo/CHEBI_35717 http://purl.obolibrary.org/obo/CHEBI_35472 http://purl.obolibrary.org/obo/CHEBI_35816 http://purl.obolibrary.org/obo/CHEBI_35623 http://purl.obolibrary.org/obo/CHEBI_48422 See more See less
InChIKey	InChIKey=UEJJHQNACJXSKW-UHFFFAOYSA-N
is metabolised by	http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_0293 http://purl.obolibrary.org/obo/dinto_0291 http://purl.obolibrary.org/obo/dinto_0269 http://purl.obolibrary.org/obo/dinto_0938 http://purl.obolibrary.org/obo/dinto_2116 See more See less
blocks	http://purl.obolibrary.org/obo/dinto_2717 http://purl.obolibrary.org/obo/dinto_0792 http://purl.obolibrary.org/obo/dinto_2116
Synonym	N-(2,6-dioxo-3-piperidyl)phthalimide Distaval Sedalis (+-)-thalidomide alpha-N-phthalylglutaramide N-phthalylglutamic acid imide 3-phthalimidoglutarimide K-17 (+-)-N-(2,6-dioxo-3-piperidyl)phthalimide thalidomide talidomida 2,6-dioxo-3-phthalimidopiperidine C13H10N2O4 Softenon alpha-phthalimidoglutarimide thalidomidum 2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione N-phthaloylglutamimide alpha-(N-phthalimido)glutarimide Talimol 1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline rac-2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione Thalidomide N-Phthalyl-glutaminsaeure-imid See more See less
xref	CiteXplore:14689682 National Drug Code Directory:59572-205-14 Wikipedia:http://en.wikipedia.org/wiki/Thalidomide Wikipedia:Thalidomide ChemSpider:5233 DrugBank:DB01041 Reaxys:30233 CiteXplore:21207098 NIST Chemistry WebBook:50-35-1 KEGG COMPOUND:C07910 CASRN:50-35-1 CiteXplore:11803357 CiteXplore:17449064 KEGG DRUG:D00754 RxList:http://www.rxlist.com/cgi/generic2/thalidom.htm BindingDB:50070114 Drugs.com:http://www.drugs.com/cdi/thalidomide.html CiteXplore:18925849 PubChem Substance:46505665 Patent:WO2013100657 CiteXplore:11349879 CiteXplore:2694291 Patent:US2012142734 CiteXplore:12724820 Patent:GB768821 CiteXplore:8469046 PharmGKB:PA451644 PubChem Compound:5426 HMDB:HMDB15175 See more See less
CASRN	50-35-1
prefixIRI	obo2:CHEBI_9513
related with	http://purl.obolibrary.org/obo/dinto_2873
SMILES	O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC=CC=C12 O=C1CCC(N2C(=O)c3ccccc3C2=O)C(=O)N1
DBname	thalidomide
InChI	InChI=1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)
DBBrand	shinnibrol bonbrain sedimide softenon talargan enterosediv neurosedyn thalin calmorex noxodyn asidon 3 nerosedyn talismol imidene thalinette shin-naito s neaufatin telagan sedin sedisperil distaval theophilcholine poly-giron grippex talimol pantosediv sedalis sedi-lab kedavon quietoplex pangul yodomin nevrodyn imida-lab neufatin sedoval slipro asmadion calmore tensival asmaval thalomid gastrinide algosediv psychotablets isomin profarmil neurodyn sedalis valgraine distoval predni-sediv contergan neosedyn corronarobetin bonbrrin polygripan psycholiquid glutanon telargean imidan pro-ban m noctosediv kevadon hippuzon quetimid telargan neosydyn sleepan neurosedym nibrol valgis distaxal ectiluran sandormin glupan neurosedin softenil See more See less
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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