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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
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| Id | http://purl.obolibrary.org/obo/CHEBI_9467
http://purl.obolibrary.org/obo/CHEBI_9467
|
|---|---|
| Preferred Name | tetrabenazine |
| Synonyms |
C19H27NO3
1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo(a)quinolizin-2-one
Nitoman
rac-(3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one
1,2,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one
tetrabenazine
Tetrabenazine
Ro 1-9569
tetrabenazinum
TBZ
Xenazine
2-oxo-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-benzoquinolizine
tetrabenazina
9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-one
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
tetrabenazine
|
|---|---|
| prefLabel |
tetrabenazine
|
| is metabolised by | |
| Definition |
A racemate consisting of equal amounts of (3R,11bR)- and (3S,11bS)-9,10-dimethoxy-3-isobutyl-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one. An adrenergic uptake inhibitor, it was formerly used as an antipsychotic, but it is now used mainly for the treatment of various movement disorders including chorea, ballism, dystonias, and tardive dyskinesia.
|
| DBBrand |
rubigen
xenazine
nitoman
|
| ATCCode |
N07XX06
|
| SMILES |
COC1=C(OC)C=C2C3CC(=O)C(CC(C)C)CN3CCC2=C1
|
| InChI |
InChI=1S/C19H27NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16H,5-7,10-11H2,1-4H3
|
| CASRN |
58-46-8
|
| prefixIRI |
obo2:CHEBI_9467
|
| Synonym |
C19H27NO3
1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo(a)quinolizin-2-one
Nitoman
rac-(3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one
1,2,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one
tetrabenazine
Tetrabenazine
Ro 1-9569
tetrabenazinum
TBZ
Xenazine
2-oxo-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-benzoquinolizine
tetrabenazina
9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-one
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|
| has effect |
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|
| binds | |
| has role | |
| DBname |
tetrabenazine
|
| InChIKey |
InChIKey=MKJIEFSOBYUXJB-UHFFFAOYSA-N
|
| subClassOf | |
| may interact with |
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| inhibits | |
| is substrate of | |
| type | |
| xref |
RxList:http://www.rxlist.com/xenazine-drug.htm
NIST Chemistry WebBook:58-46-8
National Drug Code Directory:67386-421-01
CiteXplore:20869622
PharmGKB:PA140222719
Drugs Product Database (DPD):2199270
BindingDB:50017701
CiteXplore:10686169
CiteXplore:19929707
Reaxys:9356999
CiteXplore:21487088
ChEBI:9467
Patent:US2830993
PubChem Substance:46506426
CASRN:58-46-8
ChemSpider:5796
CiteXplore:9040721
Drugs.com:http://www.drugs.com/cdi/tetrabenazine.html
Wikipedia:Tetrabenazine
CiteXplore:20442355
Wikipedia:http://en.wikipedia.org/wiki/Tetrabenazine
KEGG DRUG:D08575
DrugBank:DB04844
PubChem Compound:6018
KEGG COMPOUND:C11168
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| DBSynonym |
tetrabenazina [inn-spanish]
tbz
ro 1-9569
tetrabenzine
tetrabenazinum [inn-latin]
tetra benazin
tetrabenzaine
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| has pharmacological target |
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