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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_9150
http://purl.obolibrary.org/obo/CHEBI_9150
|
|---|---|
| Preferred Name | simvastatin |
| Synonyms |
MK-733
Simvastatine
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
simvastatin
Simvastatina
Simvastatin
Simvastatinum
C25H38O5
Zocor
2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | simvastatin
|
|---|---|
| label | simvastatin
|
| DBSynonym |
simvastatina [spanish]
simvastatin [usan:ban:inn]
simvastatine [french]
simvastatinum [latin]
|
| ATCCode | C10AA01
|
| Definition | A fatty acid ester comprising a dihydroxyheptanoic acid unit condensed into a lactone; a partially reduced naphthalene structure; and a 2,2-dimethylbutyric acyl substituent at C17. It is used as a cholesterol-lowering and anti-cardiovascular disease drug.
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| altId | CHEBI:45577
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| has effect |
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| has pharmacological target | |
| induces | |
| inhibits |
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| type | |
| has role | |
| InChIKey | InChIKey=RYMZZMVNJRMUDD-HGQWONQESA-N
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| is metabolised by |
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| AHFScode | 24:06.08
|
| Synonym | MK-733
Simvastatine
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
simvastatin
Simvastatina
Simvastatin
Simvastatinum
C25H38O5
Zocor
2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
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| xref |
RxList:http://www.rxlist.com/cgi/generic/simva.htm
Wikipedia:Simvastatin
CASRN:79902-63-9
ChEMBL:238562
DrugBank:DB00641
PharmGKB:PA451363
Beilstein:4768037
PDB:SIM
PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/zoc1500.shtml
Drugs.com:http://www.drugs.com/simvastatin.html
Patent:EP33538
Wikipedia:http://en.wikipedia.org/wiki/Simvastatin
Drugs Product Database (DPD):2253747
ChEBI:9150
Patent:US4444784
National Drug Code Directory:16714-681-01
KEGG DRUG:D00434
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| CASRN | 79902-63-9
|
| prefixIRI | obo2:CHEBI_9150
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| is transported by | |
| related with | |
| SMILES | [H][C@]12[C@H](C[C@@H](C)C=C1C=C[C@H](C)[C@@H]2CC[C@@H]1C[C@@H](O)CC(=O)O1)OC(=O)C(C)(C)CC
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| may interact with |
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| DBname | simvastatin
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| InChI | InChI=1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1
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| DBBrand |
nivelipol
denan
sivastin
rendapid
medipo
colemin
coledis
synvinolin
lipex
sinvacor
zocor
labistatin
simovil
corolin
zocord
lodales
vasotenal
pantok
cholestat
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| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
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