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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_9123
http://purl.obolibrary.org/obo/CHEBI_9123
|
|---|---|
| Preferred Name | sertraline |
| Synonyms |
cis-(+)-sertraline
(1S,4S)-sertraline
sertraline
sertralinum
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
sertralina
Sertraline
C17H17Cl2N
CP 51974
(1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine
(+)-sertraline
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | sertraline
|
|---|---|
| label | sertraline
|
| DBSynonym |
sertralinum [latin]
sertralina [spanish]
sertraline hydrochloride
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| ATCCode | N06AB06
|
| Definition | A member of the class of tetralins that is tetralin which is substituted at positions 1 and 4 by a methylamino and a 3,4-dichlorophenyl group, respectively (the S,S diastereoisomer). A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as the hydrochloride salt as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder.
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| has effect |
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| has pharmacological target | |
| inhibits |
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| type | |
| has role | |
| InChIKey | InChIKey=VGKDLMBJGBXTGI-SJCJKPOMSA-N
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| is metabolised by |
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| AHFScode | 28:16.04.20
|
| Synonym |
cis-(+)-sertraline
(1S,4S)-sertraline
sertraline
sertralinum
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
sertralina
Sertraline
C17H17Cl2N
CP 51974
(1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine
(+)-sertraline
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| xref |
CASRN:79617-96-2
CiteXplore:19502000
HMDB:HMDB05010
PharmGKB:PA451333
KEGG COMPOUND:C07246
Patent:US4536518
ChEBI:9123
RxList:http://www.rxlist.com/cgi/generic/sertral.htm
Reaxys:5753709
DrugBank:DB01104
ChemSpider:61881
National Drug Code Directory:0049-4960-30
KEGG DRUG:D02360
Drugs Product Database (DPD):2245749
CiteXplore:21823671
CASRN:5753709
Drugs.com:http://www.drugs.com/sertraline.html
NIST Chemistry WebBook:79617-96-2
PubChem Substance:46505341
ChEMBL:153616
Wikipedia:http://en.wikipedia.org/wiki/Sertraline
Wikipedia:Sertraline
PubChem Compound:68617
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| CASRN | 79617-96-2
|
| prefixIRI | obo2:CHEBI_9123
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| SMILES |
CN[C@H]1CC[C@@H](C2=CC(Cl)=C(Cl)C=C2)C2=CC=CC=C12
[H][C@]1(CC[C@H](NC)c2ccccc12)c1ccc(Cl)c(Cl)c1
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| may interact with |
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| DBname | sertraline
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| InChI | InChI=1S/C17H17Cl2N/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11/h2-6,8,10,12,17,20H,7,9H2,1H3/t12-,17-/m0/s1
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| DBBrand |
zoloft
lustral
apo-sertraline
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| subClassOf |
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