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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
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| Id | http://purl.obolibrary.org/obo/CHEBI_9011
http://purl.obolibrary.org/obo/CHEBI_9011
|
|---|---|
| Preferred Name | salmeterol |
| Synonyms |
(RS)-salmeterol
(+-)-4-hydroxy-alpha(1)-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-m-xylene-alpha,alpha(1)-diol
Salmeterol
salmeterolum
(+-)-salmeterol
(RS)-4-hydroxy-alpha(1)-({[6-(4-phenylbutoxy)hexyl]amino}methyl)-1,3-benzenedimethanol
4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)-2-(hydroxymethyl)phenol
salmeterol
C25H37NO4
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
salmeterol
|
|---|---|
| prefLabel |
salmeterol
|
| is metabolised by | |
| Definition |
A racemate consisting of equal parts of (R)- and (S)-salmeterol. It is a potent and selective beta2-adrenoceptor agonist (EC50 = 5.3 nM). Unlike other beta2 agonists, it binds to the exo-site domain of beta2 receptors, producing a slow onset of action and prolonged activation.
|
| DBBrand |
serevent
arial
aeromax
astmerole
salmetedur
|
| ATCCode |
R03AC12
|
| modulates | |
| SMILES |
OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC1=CC=CC=C1
|
| InChI |
InChI=1S/C25H37NO4/c27-20-23-18-22(13-14-24(23)28)25(29)19-26-15-7-1-2-8-16-30-17-9-6-12-21-10-4-3-5-11-21/h3-5,10-11,13-14,18,25-29H,1-2,6-9,12,15-17,19-20H2
|
| CASRN |
89365-50-4
|
| prefixIRI |
obo2:CHEBI_9011
|
| Synonym |
(RS)-salmeterol
(+-)-4-hydroxy-alpha(1)-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-m-xylene-alpha,alpha(1)-diol
Salmeterol
salmeterolum
(+-)-salmeterol
(RS)-4-hydroxy-alpha(1)-({[6-(4-phenylbutoxy)hexyl]amino}methyl)-1,3-benzenedimethanol
4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)-2-(hydroxymethyl)phenol
salmeterol
C25H37NO4
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|
| has effect |
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|
| binds | |
| has role | |
| DBname |
salmeterol
|
| InChIKey |
InChIKey=GIIZNNXWQWCKIB-UHFFFAOYSA-N
|
| subClassOf | |
| inhibits | |
| is substrate of | |
| type | |
| xref |
CiteXplore:22245487
Drugs.com:http://www.drugs.com/cdi/salmeterol.html
PubChem Compound:5152
PubChem Substance:46508024
CASRN:89365-50-4
CiteXplore:22235841
DrugBank:DB00938
CiteXplore:22192967
PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/ser1401.shtml
BindingDB:25771
Wikipedia:http://en.wikipedia.org/wiki/Salmeterol
IUPHAR:559
ChemSpider:4968
KEGG COMPOUND:C07241
CiteXplore:22231554
Patent:US4992474
Drugs Product Database (DPD):2231129
RxList:http://www.rxlist.com/cgi/generic/salmeterol.htm
Patent:DE3414752
PharmGKB:PA451300
KEGG DRUG:D05792
Guide To Pharmacology:559
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|
| DBSynonym |
salmeterolum [latin]
|
| activates | |
| AHFScode |
12:12.08.12
|
| has pharmacological target |
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