Link to this page
The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_8764
http://purl.obolibrary.org/obo/CHEBI_8764
|
|---|---|
| Preferred Name | mycophenolate mofetil |
| Synonyms |
Cellcept
2-morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
RS 61443
mycophenolic acid morpholinoethyl ester
2-(morpholin-4-yl)ethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoate
MMF
C23H31NO7
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | mycophenolate mofetil
|
|---|---|
| label | mycophenolate mofetil
|
| DBSynonym |
mycophenolic acid
mycophenylate mofetil
mpa
mmf
|
| ATCCode | L04AA06
|
| Definition | A carboxylic ester resulting from the formal condensation between the carboxylic acid group of mycophenolic acid and the hydroxy group of 2-(morpholin-4-yl)ethanol. In the liver, it is metabolised to mycophenolic acid, an immunosuppressant for which it is a prodrug. It is widely used to prevent tissue rejection following organ transplants as well as for the treatment of certain autoimmune diseases.
Mycophenolate mofetil is the 2-morpholinoethyl ester of mycophenolic acid (MPA), an immunosuppressive agent, inosine monophosphate dehydrogenase (IMPDH) inhibitor.
|
| has effect |
See more
See less
|
| DBSalt | mycophenolate sodium
|
| has pharmacological target | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=RTGDFNSFWBGLEC-SYZQJQIISA-N
|
| is metabolised by |
See more
See less
|
| AHFScode | 92:00.00
|
| Synonym | Cellcept
2-morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
RS 61443
mycophenolic acid morpholinoethyl ester
2-(morpholin-4-yl)ethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoate
MMF
C23H31NO7
See more
See less
|
| xref |
KEGG COMPOUND:C07908
CiteXplore:22310598
DrugBank:DB00688
CiteXplore:22294686
PubChem Compound:5281078
National Drug Code Directory:0781-2067-01
KEGG DRUG:D00752
Drugs.com:http://www.drugs.com/cdi/mycophenolate-mofetil.html
CiteXplore:16979992
Wikipedia:Mycophenolate_mofetil
CiteXplore:8826401
CiteXplore:11490743
CiteXplore:9274835
CiteXplore:19858585
CiteXplore:15572389
HMDB:HMDB14826
CASRN:128794-94-5
PubChem Substance:46505626
Reaxys:7500599
CiteXplore:15992049
PharmGKB:PA450566
CiteXplore:22081165
Drugs Product Database (DPD):2240347
CiteXplore:21710356
ChemSpider:4444535
CiteXplore:22460418
RxList:http://www.rxlist.com/cgi/generic3/cellcept.htm
ChEMBL:486457
ChEBI:168396
CiteXplore:22417996
Wikipedia:http://en.wikipedia.org/wiki/Mycophenolate_mofetil
CiteXplore:11099793
CiteXplore:21180633
CiteXplore:22560143
See more
See less
|
| CASRN | 128794-94-5
|
| prefixIRI | obo2:CHEBI_8764
|
| is transported by | |
| is substrate of | |
| related with | |
| SMILES |
COc1c(C)c2COC(=O)c2c(O)c1C\\C=C(/C)CCC(=O)OCCN1CCOCC1
COC1=C(C\C=C(/C)CCC(=O)OCCN2CCOCC2)C(O)=C2C(=O)OCC2=C1C
|
| may interact with |
See more
See less
|
| InChI | InChI=1S/C23H31NO7/c1-15(5-7-19(25)30-13-10-24-8-11-29-12-9-24)4-6-17-21(26)20-18(14-31-23(20)27)16(2)22(17)28-3/h4,26H,5-14H2,1-3H3/b15-4+
|
| DBBrand |
cellcept intravenous
cellcept
munoloc
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |